47 research outputs found
Assessing verticalization effects on urban safety perception
We describe an experiment with the modeling of urban verticalization effects
on perceived safety scores as obtained with computer vision on Google
Streetview data for New York City. Preliminary results suggests that for
smaller buildings (between one and seven floors), perceived safety increases
with building height, but that for high-rise buildings, perceived safety
decreases with increased height. We also determined that while height
contributing for this relation, other zonal aspects also influences the
perceived safety scores, suggesting spatial structuring also influences such
scores.Comment: 2017 SIGSPATIAL Student Research Competitio
Detangling the role of climate in vegetation productivity with an explainable convolutional neural network
Forests of the Earth are a vital carbon sink while providing an essential
habitat for biodiversity. Vegetation productivity (VP) is a critical indicator
of carbon uptake in the atmosphere. The leaf area index is a crucial vegetation
index used in VP estimation. This work proposes to predict the leaf area index
(LAI) using climate variables to better understand future productivity
dynamics; our approach leverages the capacities of the V-Net architecture for
spatiotemporal LAI prediction. Preliminary results are well-aligned with
established quality standards of LAI products estimated from Earth observation
data. We hope that this work serves as a robust foundation for subsequent
research endeavours, particularly for the incorporation of prediction
attribution methodologies, which hold promise for elucidating the underlying
climate change drivers of global vegetation productivity.Comment: 7 pages, 2 figures, submitted to Tackling Climate Change with Machine
Learning at NeurIPS 202
Seismic behaviour of portuguese rammed earth buildings
Rammed earth is one of the oldest building materials in the world and is present in the
Portugal with a particular focus in the South of the country. The mechanical properties and
the structural behaviour of rammed earth constructions have been the subject of study of
many researchers in the recent years. This study is part of a broader research on vernacular
seismic culture in Portugal. Numerical analyses were carried out on a rammed earth masonry
construction representative of the vernacular heritage of Alentejo region. Variations in the
geometry, constructive characteristics and material properties were implemented and the main
conclusions of the non-linear static and modal analysis are presented. Analysing the damage
framework allowed interpreting the weaknesses of this type of constructions and consider the
most appropriate reinforcement methodologies
VII CONGRESSO NACIONAL DE ENGENHARIA MECÂNICA
Diversos estudos de análise térmica vêm sendo realizados tendo como base a primeira e segunda lei da
termodinâmica, essa abordagem fornece resultados que se complementam e propicia a tomada de decisão no que se
diz respeito à eficiência em operação de um sistema térmico, como também a identificação dos componentes do
sistema onde um gestor de manutenção deve focar seus esforços para atingir maiores ganhos de eficiência. A
metodologia da análise exergética foi aplicada a uma central de água gelada (Chiller), que funciona com o ciclo de
refrigeração por compressão de vapor, localizada em um centro de tecnologia de Salvador/BA. Foi utilizada a
plataforma EES (Engineering Equation Solver) para solução dos sistemas de equações. A análise identificou os
compressores do sistema como os principais responsáveis pelas perdas exergéticas, bem como uma eficiência de
segunda lei do ciclo de apenas 21%. Por fim foram quantificados os custos das irreversibilidades e comparados com o
custo da energia elétrica para acionamento dos compressores. Por fim foi possível demonstrar que a eficiência de
primeira lei (COP), apesar de muito difundido, não reflete completamente o real desempenho energético do ciclo,
sendo necessário complementá-lo com o estudo pela segunda lei da termodinâmica.São Lui
Improving the reproducibility in geoscientific papers: lessons learned from a Hackathon in climate science
In this paper, we explore the crucial role and challenges of computational reproducibility in geosciences, drawing insights from the Climate Informatics Reproducibility Challenge (CICR) in 2023. The competition aimed at (1) identifying common hurdles to reproduce computational climate science; and (2) creating interactive reproducible publications for selected papers of the Environmental Data Science journal. Based on lessons learned from the challenge, we emphasize the significance of open research practices, mentorship, transparency guidelines, as well as the use of technologies such as executable research objects for the reproduction of geoscientific published research. We propose a supportive framework of tools and infrastructure for evaluating reproducibility in geoscientific publications, with a case study for the climate informatics community. While the recommendations focus on future CIRCs, we expect they would be beneficial for wider umbrella of reproducibility initiatives in geosciences
Biogas production from microalgal biomass produced in the tertiary treatment of urban wastewater: assessment of seasonal variations
The valorization of microalgal biomass produced during wastewater treatment has the potential to mitigate treatment costs. As contaminated biomass (e.g., with pharmaceuticals, toxic metals, etc.) is often generated, biogas production is considered an effective valorization option. The biomass was obtained from a pilot facility of photobioreactors for tertiary wastewater treatment. The pilots were run for one year with naturally formed microalgal consortia. The biogas was generated in 70 mL crimp-top vials at 35 °C, quantified with a manometer and the methane yield measured by gas chromatography. A maximum biogas production of 311 mL/g volatile solids (VS) with a methane yield of 252 mL/g VS was obtained with the spring samples. These rather low values were not improved using previous thermo-acidic hydrolysis, suggesting that the low intrinsic biodegradable organic matter content of the consortia might be the cause for low yield. Considering the total volume of wastewater treated by this plant and the average amount of methane produced in this study, the substitution of the current tertiary treatment with the one here proposed would reduce the energy consumption of the plant by 20% and create an energy surplus of 2.8%. The implementation of this system would therefore contribute towards meeting the ambitious decarbonization targets established by the EU.info:eu-repo/semantics/publishedVersio
Maternal complications following endoscopic surgeries in fetal Medicine
OBJETIVO: descrever as complicações maternas decorrentes dos procedimentos endoscópicos terapêuticos em Medicina fetal, realizados em um centro universitário no Brasil. MÉTODOS: estudo observacional retrospectivo que incluiu gestantes atendidas no período de Abril de 2007 a Maio de 2010. Esses casos foram submetidos aos seguintes procedimentos: ablação vascular placentária com laser (AVPL) por síndrome de transfusão feto-fetal (STFF) grave; oclusão traqueal fetal (OTF) e retirada de balão traqueal por via endoscópica por hérnia diafragmática congênita (HDC) grave e AVPL, com ou sem cauterização bipolar do cordão umbilical, por síndrome da perfusão arterial reversa (SPAR) em gêmeo acárdico. As principais variáveis descritas para cada condição clínica/tipo de cirurgia foram as complicações maternas e a sobrevida (alta do berçário) do neonato/lactente. RESULTADOS: cinquenta e seis gestantes foram submetidas a 70 procedimentos: STFF grave (34 pacientes; 34 cirurgias); HDC grave (16 pacientes; 30 cirurgias) e SPAR (6 pacientes; 6 cirurgias). Entre as 34 gestantes tratadas com AVPL por STFF, duas (2/34=5,9%) apresentaram perda de líquido amniótico para a cavidade peritoneal e sete (7/34=20,6%) tiveram abortamento após os procedimentos. A sobrevida de pelo menos um gêmeo foi de 64,7% (22/34). Entre as 30 intervenções realizadas para HDC, houve perda de líquido amniótico para a cavidade peritoneal materna em um caso (1/30=3,3%) e rotura prematura pré-termo de membranas após três (3/30=30%) fetoscopias para retirada do balão traqueal. A sobrevida com alta do berçário foi de 43,8% (7/16). Entre os seis casos de SPAR, houve sangramento materno para a cavidade peritoneal após uma cirurgia (1/6=16,7%) e a sobrevida com alta do berçário foi de 50% (3/6). CONCLUSÕES: em concordância com os dados disponíveis na literatura, em nosso centro, os benefícios relacionados às intervenções endoscópicas terapêuticas em casos de STFF, HDC e SPAR parecem superar os riscos de complicações maternas que, raramente, foram consideradas graves.PURPOSE: to describe the maternal complications due to therapeutic endoscopic procedures in fetal Medicine performed at an university center in Brazil. METHODS: retrospective observational study including patients treated from April 2007 to May 2010 who underwent laser ablation of placental vessels (LAPV) for severe twin-twin transfusion syndrome (TTTS); fetal tracheal occlusion (FETO) and endoscopic removal of tracheal balloon in cases of severe congenital diaphragmatic hernia (CDH); LAPV with or without bipolar coagulation of the umbilical cord in cases of twin reversed arterial perfusion (TRAP) sequence. The main variables described for each disease/type of surgery were maternal complications and neonatal survival (discharge from nursery). RESULTS: fifty-six patients underwent 70 procedures: Severe TTTS (34 patients; 34 surgeries); severe CDH (16 patients; 30 surgeries), and TRAP sequence (6 patients; 6 surgeries). Among 34 women who underwent LAPV for TTTS, two (2/34=5.9%) experienced amniotic fluid leakage to the peritoneal cavity and seven (7/34=20.6%) miscarried after the procedure. Survival of at least one twin was 64.7% (22/34). Among 30 interventions performed in cases of CDH, there was amniotic fluid leakage into the maternal peritoneal cavity in one patient (1/30=3.3%) and premature preterm rupture of membranes after three (3/30=30%) fetoscopies for removal of the tracheal balloon. Infant survival with discharge from nursery was 43.8% (7/16). Among six cases of TRAP sequence, there was bleeding into the peritoneal cavity after surgery in one patient (1/6=16.7%) and neonatal survival with discharge from nursery was 50% (3/6). CONCLUSIONS: in agreement with the available data in literature, at our center, the benefits related to therapeutic endoscopic interventions for TTTS, CDH and TRAP sequence seem to overcome the risks of maternal complications, which were rarely considered severe
Maternal complications following endoscopic surgeries in fetal Medicine
Descrever as complicações maternas decorrentes dos procedimentos endoscópicos terapêuticos em Medicina fetal, realizados em um centro universitário no Brasil. Estudo observacional retrospectivo que incluiu gestantes atendidas no período de Abril de 2007 a Maio de 2010. Esses casos foram submetidos aos seguintes procedimentos: ablação vascular placentária com laser (AVPL) por síndrome de transfusão feto-fetal (STFF) grave; oclusão traqueal fetal (OTF) e retirada de balão traqueal por via endoscópica por hérnia diafragmática congênita (HDC) grave e AVPL, com ou sem cauterização bipolar do cordão umbilical, por síndrome da perfusão arterial reversa (SPAR) em gêmeo acárdico. As principais variáveis descritas para cada condição clínica/tipo de cirurgia foram as complicações maternas e a sobrevida (alta do berçário) do neonato/lactente. Cinquenta e seis gestantes foram submetidas a 70 procedimentos: STFF grave (34 pacientes; 34 cirurgias); HDC grave (16 pacientes; 30 cirurgias) e SPAR (6 pacientes; 6 cirurgias). Entre as 34 gestantes tratadas com AVPL por STFF, duas (2/34=5,9%) apresentaram perda de líquido amniótico para a cavidade peritoneal e sete (7/34=20,6%) tiveram abortamento após os procedimentos. A sobrevida de pelo menos um gêmeo foi de 64,7% (22/34). Entre as 30 intervenções realizadas para HDC, houve perda de líquido amniótico para a cavidade peritoneal materna em um caso (1/30=3,3%) e rotura prematura pré-termo de membranas após três (3/30=30%) fetoscopias para retirada do balão traqueal. A sobrevida com alta do berçário foi de 43,8% (7/16). Entre os seis casos de SPAR, houve sangramento materno para a cavidade peritoneal após uma cirurgia (1/6=16,7%) e a sobrevida com alta do berçário foi de 50% (3/6). Em concordância com os dados disponíveis na literatura, em nosso centro, os benefícios relacionados às intervenções endoscópicas terapêuticas em casos de STFF, HDC e SPAR parecem superar os riscos de complicações maternas que, raramente, foram consideradas graves326260266To describe the maternal complications due to therapeutic endoscopic procedures in fetal Medicine performed at an university center in Brazil. Retrospective observational study including patients treated from April 2007 to May 2010 who underwent laser ablation of placental vessels (LAPV) for severe twin-twin transfusion syndrome (TTTS); fetal tracheal occlusion (FETO) and endoscopic removal of tracheal balloon in cases of severe congenital diaphragmatic hernia (CDH); LAPV with or without bipolar coagulation of the umbilical cord in cases of twin reversed arterial perfusion (TRAP) sequence. The main variables described for each disease/type of surgery were maternal complications and neonatal survival (discharge from nursery). Fifty-six patients underwent 70 procedures: Severe TTTS (34 patients; 34 surgeries); severe CDH (16 patients; 30 surgeries), and TRAP sequence (6 patients; 6 surgeries). Among 34 women who underwent LAPV for TTTS, two (2/34=5.9%) experienced amniotic fluid leakage to the peritoneal cavity and seven (7/34=20.6%) miscarried after the procedure. Survival of at least one twin was 64.7% (22/34). Among 30 interventions performed in cases of CDH, there was amniotic fluid leakage into the maternal peritoneal cavity in one patient (1/30=3.3%) and premature preterm rupture of membranes after three (3/30=30%) fetoscopies for removal of the tracheal balloon. Infant survival with discharge from nursery was 43.8% (7/16). Among six cases of TRAP sequence, there was bleeding into the peritoneal cavity after surgery in one patient (1/6=16.7%) and neonatal survival with discharge from nursery was 50% (3/6). In agreement with the available data in literature, at our center, the benefits related to therapeutic endoscopic interventions for TTTS, CDH and TRAP sequence seem to overcome the risks of maternal complications, which were rarely considered sever
Maternal complications following endoscopic surgeries in fetal Medicine
OBJETIVO: descrever as complicações maternas decorrentes dos procedimentos endoscópicos terapêuticos em Medicina fetal, realizados em um centro universitário no Brasil. MÉTODOS: estudo observacional retrospectivo que incluiu gestantes atendidas no período de Abril de 2007 a Maio de 2010. Esses casos foram submetidos aos seguintes procedimentos: ablação vascular placentária com laser (AVPL) por síndrome de transfusão feto-fetal (STFF) grave; oclusão traqueal fetal (OTF) e retirada de balão traqueal por via endoscópica por hérnia diafragmática congênita (HDC) grave e AVPL, com ou sem cauterização bipolar do cordão umbilical, por síndrome da perfusão arterial reversa (SPAR) em gêmeo acárdico. As principais variáveis descritas para cada condição clínica/tipo de cirurgia foram as complicações maternas e a sobrevida (alta do berçário) do neonato/lactente. RESULTADOS: cinquenta e seis gestantes foram submetidas a 70 procedimentos: STFF grave (34 pacientes; 34 cirurgias); HDC grave (16 pacientes; 30 cirurgias) e SPAR (6 pacientes; 6 cirurgias). Entre as 34 gestantes tratadas com AVPL por STFF, duas (2/34=5,9%) apresentaram perda de líquido amniótico para a cavidade peritoneal e sete (7/34=20,6%) tiveram abortamento após os procedimentos. A sobrevida de pelo menos um gêmeo foi de 64,7% (22/34). Entre as 30 intervenções realizadas para HDC, houve perda de líquido amniótico para a cavidade peritoneal materna em um caso (1/30=3,3%) e rotura prematura pré-termo de membranas após três (3/30=30%) fetoscopias para retirada do balão traqueal. A sobrevida com alta do berçário foi de 43,8% (7/16). Entre os seis casos de SPAR, houve sangramento materno para a cavidade peritoneal após uma cirurgia (1/6=16,7%) e a sobrevida com alta do berçário foi de 50% (3/6). CONCLUSÕES: em concordância com os dados disponíveis na literatura, em nosso centro, os benefícios relacionados às intervenções endoscópicas terapêuticas em casos de STFF, HDC e SPAR parecem superar os riscos de complicações maternas que, raramente, foram consideradas graves.PURPOSE: to describe the maternal complications due to therapeutic endoscopic procedures in fetal Medicine performed at an university center in Brazil. METHODS: retrospective observational study including patients treated from April 2007 to May 2010 who underwent laser ablation of placental vessels (LAPV) for severe twin-twin transfusion syndrome (TTTS); fetal tracheal occlusion (FETO) and endoscopic removal of tracheal balloon in cases of severe congenital diaphragmatic hernia (CDH); LAPV with or without bipolar coagulation of the umbilical cord in cases of twin reversed arterial perfusion (TRAP) sequence. The main variables described for each disease/type of surgery were maternal complications and neonatal survival (discharge from nursery). RESULTS: fifty-six patients underwent 70 procedures: Severe TTTS (34 patients; 34 surgeries); severe CDH (16 patients; 30 surgeries), and TRAP sequence (6 patients; 6 surgeries). Among 34 women who underwent LAPV for TTTS, two (2/34=5.9%) experienced amniotic fluid leakage to the peritoneal cavity and seven (7/34=20.6%) miscarried after the procedure. Survival of at least one twin was 64.7% (22/34). Among 30 interventions performed in cases of CDH, there was amniotic fluid leakage into the maternal peritoneal cavity in one patient (1/30=3.3%) and premature preterm rupture of membranes after three (3/30=30%) fetoscopies for removal of the tracheal balloon. Infant survival with discharge from nursery was 43.8% (7/16). Among six cases of TRAP sequence, there was bleeding into the peritoneal cavity after surgery in one patient (1/6=16.7%) and neonatal survival with discharge from nursery was 50% (3/6). CONCLUSIONS: in agreement with the available data in literature, at our center, the benefits related to therapeutic endoscopic interventions for TTTS, CDH and TRAP sequence seem to overcome the risks of maternal complications, which were rarely considered severe.32626026
New 99mTc-Labeled Digitoxigenin Derivative for Cancer Cell Identification
In recent years, cardiac glycosides (CGs) have been investigated as potential antiviral and anticancer drugs. Digitoxigenin (DIG) and other CGs have been shown to bind and inhibit Na+/K+-adenosinetriphosphatase (ATPase). Tumor cells show a higher expression rate of the Na+/K+-ATPase protein or a stronger affinity towards the binding of CGs and are therefore more prone to CGs than non-tumor cells. Cancer imaging techniques using radiotracers targeted at specific receptors have yielded successful results. Technetium-99m (99mTc) is one of the radionuclides of choice to radiolabel pharmaceuticals because of its favorable physical and chemical properties along with reasonable costs. Herein, we describe a new Na+/K+-ATPase targeting radiotracer consisting of digitoxigenin and diethylenetriaminepentaacetic acid (DTPA), a bifunctional chelating ligand used to prepare 99mTc-labeled complexes, and its evaluation as an imaging probe. We report the synthesis and characterization of the radiolabeled compound including stability tests, blood clearance, and biodistribution in healthy mice. Additionally, we investigated the binding of the compound to A549 human non-small-cell lung cancer cells and the inhibition of the Na+/K+-ATPase by the labeled compound in vitro. The 99mTc-labeled DTPA–digitoxigenin (99mTc-DTPA–DIG) compound displayed high stability in vitro and in vivo, a fast renal excretion, and a specific binding towards A549 cancer cells in comparison to non-tumor cells. Therefore, 99mTc-DTPA–DIG could potentially be used for non-invasive visualization of tumor lesions by means of scintigraphic imaging