9 research outputs found

    Role of age and comorbidities in mortality of patients with infective endocarditis

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    [Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

    Outpatient Parenteral Antibiotic Treatment vs Hospitalization for Infective Endocarditis: Validation of the OPAT-GAMES Criteria

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    Nuevas modalidades de subtitulación aplicadas a la traducción de referentes culturales en productos audiovisuales televisivos en la combinación chino - español: Aplicación y estudio de recepción de la serie documental ⾆尖上的中国 (A bite of china)

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    La hipótesis general formulada para guiar la investigación de este trabajo fin de máster es que la asimilación de algunas de las tendencias y técnicas de traducción presentes en nuevas modalidades de subtitulación (profesional o no-profesional) pueden resultar más adecuadas para la subtitulación de productos audiovisuales televisivos de marcado carácter cultural. Más allá de la recopilación y análisis de un marco teórico que nos aportará un soporte de resultados descriptivos, la comprobación de la hipótesis planteada estará sustentada en una muestra de subtitulación del producto audiovisual escogido y un estudio de recepción a través de encuestas que generen datos e información suficientes y relevantes para aceptarla

    MATCH THESE PAIRS OF WORDS

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    CLOTHING CROSSWORDS

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    Role of age and comorbidities in mortality of patients with infective endocarditis.

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    The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups: A total of 3120 patients with IE (1327  There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in th

    Infective Endocarditis in Patients With Bicuspid Aortic Valve or Mitral Valve Prolapse

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    Mural Endocarditis: The GAMES Registry Series and Review of the Literature

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